Human Resources

Postdoctoral Research Assistant (Wellcome Trust) - QMUL7630

Department: School of Engineering & Materials Science
Salary: £32,052 (Grade 4)
Reference: QMUL7630
Location: Mile End
Date posted: 03-Dec-2015
Closing date: 07-Jan-2016

Job profile Apply online


Applications are sought for a Postdoctoral Research Assistant position in the group of Dr Pavel Novak to undertake innovative research into mechanisms of mechanotransduction in primary cilia using state-of-the-art techniques in nanoscale physiology. The post will be embedded in the vibrant, multidisciplinary environment of School of Engineering and Materials Science, Queen Mary University of London, in collaboration with Professor Martin Knight, and supported by The Wellcome Trust Seed Award.

The aim of the project is to combine the latest technology in scanning probe microscopy, nanopipette techniques, and electrophysiology to break the existing resolution barrier in direct stimulation and recording of channel and receptor activity along the fine structure of primary cilia. The established technique will be used to acquire unique data on the spatial distribution and function of channels and receptors in primary cilia to support subsequent research applications aimed at understanding the reorganization of sensing in ciliated cells in health and disease.

The successful candidate will have a PhD or equivalent in biophysics, bioengineering or similar subjects. Previous experience in electrophysiology, patch – clamp recordings, or scanning probe microscopy is highly desirable. During the project the PDRA will gain a unique experience with the emerging technique of scanning ion conductance microscopy and its ground-breaking applications in nanoscale physiology. In addition, the PDRA will have opportunities to interact with collaborating research groups at Imperial College London and University of Cambridge at the forefront of development and applications of scanning ion conductance microscopy.

The post is full time, fixed term appointment for 2 years, with an expected start date of 1st February 2016. Starting salary will be £32,052 per annum, inclusive of London Allowance. Benefits include 30 days annual leave, defined benefit pension scheme and interest-free season ticket loan.

Candidates must be able to demonstrate their eligibility to work in the UK in accordance with the Immigration, Asylum and Nationality Act 2006. Where required this may include entry clearance or continued leave to remain under the Points Based Immigration Scheme.

Informal enquiries should be addressed to Dr Pavel Novak at or on +44 (0) 020 7882 5183.

Details about the school can be found at


To apply for the role, please click the ‘apply’ button below.

The closing date for applications is 07 January 2016. Interviews are expected to be held shortly thereafter.

Valuing Diversity & Committed to Equality

Apply online