Department: Barts Cancer Institute
Salary: £38,084 - £40,194 (Grade 5)
Location: Charterhouse Square
Date posted: 26-Jan-2021
Closing date: 24-Feb-2021
Centre for Cancer Evolution and Computational Biology
Post title: Postdoctoral Research Assistant Post ref: QMUL23342
About the Role
Dr. Benjamin Werner from the Barts Cancer Institute in London is searching for a Post Doc candidate to join his team at Queen Mary University in London. The Postdoctoral Research Assistant position is funded for 3 years by the Human Frontiers in Science Program and part of a joined collaboration (ADAPTSEX) with Thorsten Reusch from Geomar in Kiel (Germany) and Iliana Baums from Penn State University (USA). In this international collaboration we develop and integrate population genetics theory on somatic evolution with genomic/experimental data on seagrasses and corals to understand the role of somatic evolution on the adaptation of these long lived asexual organisms.
The Post Doc positions searches for a mathematical/computational biologist with knowledge in cancer genetic population theory and ideally experience with cancer genomic data. The aim is to further develop the ideas and concepts of genetic somatic evolution and integrate those models with cancer, seagrass and coral data.
About the School/Department/Institute/Project
All multicellular species are genetic mosaics, composed of cell lines that differ in their genotype owing to somatic mutations. Such intra-organismal genetic heterogeneity is often viewed negatively, resulting in mutational load, fitness decreases and senescence. Arguably the most prominent case is cancer that is now commonly viewed as evolutionary process. Within this framework, recent progress in modeling adaptive dynamics was made, describing important sub-clonal genetic structure, and identify driver and passenger mutations in growing cancer tumors. To exchange knowledge among the biomedical field and the evolutionary ecology of free-living, “natural” clones, two evolutionary ecologists working in plant (Thorsten Reusch) and coral (Iliana Baums) evolutionary ecology and genomics have therefore teamed up with me. In ADAPTASEX, we will develop a joint analytical framework to comprehensively describe adaptive dynamics in multicellular clonal systems by bringing together researchers from cancer to corals and seagrasses.
About Queen Mary
At Queen Mary University of London, we believe that a diversity of ideas helps us achieve the previously unthinkable.
We offer competitive salaries, access to a generous pension scheme, 30 days’ leave per annum (pro-rata for part-time/fixed-term), a season ticket loan scheme and access to a comprehensive range of personal and professional development opportunities. In addition, we offer a range of work life balance and family friendly, inclusive employment policies, flexible working arrangements, and campus facilities including an on-site nursery at the Mile End campus.
The post is based at the Charterhouse Square campus in London. It is full time (35 hours per week), fixed term appointment for 3 years, with an expected start date of 1st April 2020. The starting salary will be Grade 5, in the range of £38,084 - £40,194 per annum, inclusive of London Allowance.
Queen Mary’s commitment to our diverse and inclusive community is embedded in our appointments processes. Reasonable adjustments will be made at each stage of the recruitment process for any candidate with a disability. We are open to considering applications from candidates wishing to work flexibly.
Informal enquiries should be addressed to Dr Benjamin Werner at firstname.lastname@example.org.
The closing date for applications is Tuesday 24th February 2021.
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