Department: Barts Cancer Institute
Salary: £34,220 - £43,602 per annum
Location: Charterhouse Square
Date posted: 17-Dec-2020
Closing date: 17-Jan-2021
About the Role
We are seeking a Postdoctoral Research Assistant to join the group of Dr Mirjana Efremova in the Centre for Genomics and Computational Biology, Barts Cancer Institute.
Essential requirements for this post include a PhD in a relevant biological subject, strong background in molecular biology techniques and experience with high-throughput next-generation sequencing methodologies. Experience/interest in single-cell omics technologies and/or animal models is desirable.
About the School/Department/Institute/Project
We are seeking a postdoctoral research assistant to join the group of Dr Mirjana Efremova in the Centre for Genomics and Computational Biology, to work in a Barts Charity funded position. The PDRA will investigate the role of the microenvironment during the complex process of metastatic colonisation and establishment of the metastatic niche. We recently developed a framework for inference of cell-cell communication networks (Efremova et al. Nature Protocols, 2020; Vento-Tormo*, Efremova* et al. Nature, 2018) and applied it to unravel the complex interplay in the evolving tumour microenvironment in melanoma (Davidson*, Efremova* et al., Cell Reports, 2020). In this project, we aim to integrate cutting edge single-cell multi-omics methods and spatial proteomics towards understanding both the intrinsic traits and microenvironmental cues that drive establishment of organ-specific metastatic niches. The project will combine the analysis of mouse models through collaborations and patient samples, focusing on melanoma, pancreatic and colorectal cancer. The appointed PDRA will be integrated into a multidisciplinary team and will collaborate with bioinformaticians, experimentalists and clinicians. The position also offers an opportunity to learn computational analysis of transcriptomic and epigenetic data with the help of methods and techniques established in our lab.
We offer competitive salaries, access to a generous pension scheme, 30 days’ leave per annum (pro-rata for part-time/fixed-term), a season ticket loan scheme and access to a comprehensive range of personal and professional development opportunities. In addition, we offer a range of work life balance and family friendly, inclusive employment policies, flexible working arrangements, and campus facilities including an on-site nursery at the Mile End campus.
The post is based at the Charterhouse Square Campus in London. It is full time (35 hours per week), fixed term appointment for 3 years, to start as soon as possible. The starting salary will be Grade 4/5, in the range of £34,220 - £43,062 per annum, inclusive of London Allowance.
Queen Mary’s commitment to our diverse and inclusive community is embedded in our appointments processes. Reasonable adjustments will be made at each stage of the recruitment process for any candidate with a disability. We are open to considering applications from candidates wishing to work flexibly.
Informal enquiries should be addressed to Dr Mirjana Efremova at email@example.com.
To apply for the role, please click the ‘apply’ button below.
The closing date for applications is Sunday 17th January 2020.
Interviews are expected to be held early in January or February.
The School of Medicine and Athena SWAN Charter for Women in Science.
The School of Medicine holds a Silver Athena SWAN Award. We are committed to the equality of opportunities and to advancing women’s careers. We have policies to support staff returning from long-term absence, for flexible arrangements for staff with parental responsibilities and for childcare support. As part of the School’s commitment to the Athena SWAN principles we strongly encourage applications from women.
Valuing Diversity & Committed to Equality