Department: Barts Cancer Institute
Salary: £34,220 - £37,076 per annum (Grade 4)
Location: Charterhouse Square
Date posted: 19-Nov-2020
Closing date: 17-Dec-2020
Barts Cancer Institute
Centre for Haemato-Oncology
POSTDOCTORAL RESEARCH ASSISTANT
Applications are sought for a talented and highly motivated Postdoctoral Researcher to join the translational lymphoma laboratory of Dr Jessica Okosun. Work in our group focusses on B-cell non-Hodgkin’s lymphomas. Our main interests are in: (i) deciphering the molecular events that govern tumour initiation and progression; (ii) understanding the impact of intra-tumour heterogeneity and clonal evolution and ultimately (iii) identifying and developing predictive and prognostic biomarker tools. We utilise primary lymphoma samples from our long-standing tissue bank and national clinical trials, high-resolution omic technologies and molecular biology techniques in our studies.
The successful applicant will lead a project using single-cell methodologies (scRNA-seq/scDNA-seq/scATAC-seq) to interrogate tumoral and immune microenvironment heterogeneity and clonal evolution in follicular lymphoma as it transforms to a more aggressive lymphoma, whilst contributing to a number of key projects within our areas of interest. As a translational research laboratory, we have established close multidisciplinary collaborations with bioinformaticians, clinicians, haemato-pathologists and the wider UK Lymphoma Clinical Trials network.
The research will be based in the Centre for Haemato-Oncology, Barts Cancer Institute, within the Barts and The London School of Medicine and Dentistry, Queen Mary, University of London.
Essential requirements for this post include a PhD in a cancer biology, genetics, immunology or related area together with strong technical expertise in genomics, molecular or cellular biology. Experience with multi-colour flow cytometry, single-cell approaches and computational biology/bioinformatics would be advantageous. A demonstrated ability to communicate well, work within a team and maintain good laboratory records are also essential.
The post is full time and funded for 2 years in the first instance (with the possibility of an extension), starting from January 2021 or earlier if available. Starting salary will be commensurate with experience and in the range Research Grade 4, in the range of £34,220 to £37,076 per annum inclusive of London Allowance.
We offer competitive salaries, access to a generous pension scheme, 30 days’ leave per annum (pro-rata for part-time/fixed-term), a season ticket loan scheme and access to a comprehensive range of personal and professional development opportunities. In addition, we offer a range of work life balance and family friendly, inclusive employment policies, flexible working arrangements, and campus facilities including an on-site nursery at the Mile End campus.
The Barts Cancer Institute requires that applicants invited for interview will need to provide all certificates to confirm their qualifications (specified in the Job Description).
Candidates must be able to demonstrate their eligibility to work in the UK in accordance with the Immigration, Asylum and Nationality Act 2006. Where required this may include entry clearance or continued leave ot remain under the Points Based Immigration Scheme.
Informal enquiries to discuss this post and project are especially highly encouraged, including arrangements to visit the Institute/Centre, and can be made to Dr Jessica Okosun tel: +44 (0)20 78828814 or email firstname.lastname@example.org
Details about Barts Cancer Institute can be found at www.bci.qmul.ac.uk
To apply for the role, please click the ‘apply’ button below.
The closing date for applications is 17th December 2020. Interviews are expected to be held shortly thereafter.
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