Human Resources

Postdoctoral Research Assistant - QMUL16575

Department: Barts Cancer Institute
Salary: £33,615 ¿ £37,411 (Grade 4)
Reference: QMUL16575
Date posted: 31-Oct-2018
Closing date: 14-Nov-2018

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Barts Cancer Institute

Centre for Haemato-Oncology

Post doctoral Research Assitant

The Barts Cancer Institute (BCI) is a Cancer Research UK Centre of Excellence whose work aims to transform the lives of those with and at risk of cancer throughinnovative research in the laboratory, in patients and in populations. It is one of six institutes within The School of Medicine and Dentistry.

We are seeking a highly motivated and career-oriented postdoctoral fellow to join our leukaemia biology team at Barts Cancer Institute. Our groups’ aims to establish fundamental insights into the biology of leukaemia initiating cells (LICs) in ALL enabling the development of strategies that preferentially target and eliminate these cellular drivers of disease progression. The research will employ special methodology and expertise in a range of techniques ranging from functional modelling of patient derived xenografts, multiplex immune imaging as well as micro CT to illuminate key ALL-Bone Marrow Microenvironment interactions. Cellular biology studies will be complimented by high resolution proteomic and molecular profiling to provide a comprehensive and coherent view of major mechanistic nodes orchestrating ALL dormancy.

The successful applicant will will work within an integrated programme of ALL research which includes pre-clinical efficacy studies and molecular interrogations of ALL resistance to broaden their experience and skills portfolio. Potential candidates must have practical experience in cellular and molecular biology, flow cytometry and mouse models.  Practical knowledge in bioinformatics data mining is a plus. The research will be based in the Centre for Haemato-Oncology Barts Cancer Institute, within the Barts and The London School of Medicine and Dentistry, Queen Mary, University of London.

Essential requirements for this post include practical experience in cellular and molecular biology, flow cytometry and mouse models.   A demonstrated ability to communicate well, work within a team and maintain good laboratory records are also essential.

The post is full time and permanent for 2 years .  Starting salary will be in the salary range of £33,615 – £37,411per annum inclusive of London Allowance. Benefits include 30 days annual leave (if part time – pro rata), pension scheme and an interest free season ticket loan.

The Barts Cancer Institute requires that applicants invited for interview will need to provide all certificates to confirm their qualifications (specified in the Job Description).

Candidates must be able to demonstrate their eligibility to work in the UK in accordance with the Immigration, Asylum and Nationality Act 2006.  Where required this may include entry clearance or continued leave ot remain under the Points Based Immigration Scheme.

Informal enquiries about this post, including arrangements to visit the Institute/Centre, can be made to Dr Bela Wrench Tel: 0207 882 2277or email

Details about Barts Cancer Institute can be found at

To apply, please visit the Human Resources website on and search for reference QMUL16575.

 [To apply and for full job details including a job description and person specification please visit and search for reference QMUL16575.}

The Closing date is 14th November 2018.

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