Department: Centre for Stem Cells in Cancer & Ageing, Barts Cancer Institute
Salary: 29,936 - 36,064 (Grade 4)
Date posted: 30-Mar-2017
Closing date: 29-Apr-2017
Barts Cancer Institute
Centre for Cancer, Stem Cells & Ageing
Applications are sought for a Research Technician position within the vibrant and interdisciplinary SU2C Lustgarten CRUK Pancreatic Cancer Dream Team
“Reprogramming of Transcriptional Circuitry to Control Pancreatic Cancer”.
Traditional therapies simply targeting the bulk epithelial cancer cells have failed due to confounding effects attributed to distinct subpopulations of highly chemoresistant cancer stem cells and the complex microenvironment that protects and fuels the cancer. We propose that a global approach is needed to break the cycle of incremental gains and make a significant breakthrough in treating pancreatic cancer. We have developed novel therapeutic regimens that will now be tested clinically in proof-of-principle trials with in-depth analysis of (liquid) tumor biopsies to understand how the therapy impacts the tumor's biology in patients. A set of innovative technologies has been developed for this purpose and and the successful candidate will undergo comprehensive training by senior scientists and technicians as required. The lab is based in the Centre for Stem Cells in Cancer & Ageing, Barts Cancer Institute, within the Barts and The London School of Medicine and Dentistry, Queen Mary, University of London.
A BSc degree in a biological subject is essential. Other essential requirements for this post include knowledge of cancer cell biology and advanced molecular techniques. Specific interest in studying the epigenetic regulation of cancer stem cells with minimal supervision and experience in flow cytometry, cell sorting, confocal microscopy and/or primary cell culture are desireable. A strong ability to communicate well, work within a team and maintain good laboratory records are also essential.
The post is full time for a period of 2 years. Salary will be in the Grade 4 Research range of £29,936 - £36,064 per annum, inclusive of London Allowance, commensurate with qualifications and experience. Benefits include 30 days’ annual leave, defined benefit pension scheme and interest-free season ticket loan. The Barts Cancer Institute requires that applicants invited for interview will need to provide all certificates to confirm their qualifications (specified in the Job Description).
Candidates must be able to demonstrate their eligibility to work in the UK in accordance with the Immigration, Asylum and Nationality Act 2006. Where required this may include entry clearance or continued leave to remain under the Points Based Immigration Scheme.
Informal enquiries about this post, including arrangements to visit the Institute/Centre, can be made to Dr. David Propper (email@example.com) or Prof. Christopher Heeschen (firstname.lastname@example.org)
Details about Barts Cancer Institute can be found at www.bci.qmul.ac.uk
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Application enquiries can be directed to email@example.com
The closing date is 29 April 2017 and interviews are likely to be held shortly thereafter.
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