Human Resources

Postdoctoral Research Fellow ¿ Cellular Immunology - QMUL12664

Department: William Harvey Research Institute
Salary: £32,956 - £34,764 per annum (Grade 4)
Reference: QMUL12664
Date posted: 11-Sep-2017
Closing date: 11-Oct-2017

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William Harvey Research Institute

Centre for Experimental Medicine & Rheumatology

Postdoctoral Research Fellow – Cellular Immunology

We seek a Postdoctoral Research Fellow to join a 55 strong research team of scientists, clinicians and clinical trial staff dedicated to Inflammation and Rheumatology Research at the Centre for Experimental Medicine & Rheumatology (EMR), Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, EC1, led by Professor Costantino Pitzalis. EMR opened in May 2007 and the Centre is focused on the development of innovative therapeutic and diagnostic approaches to inflammatory and degenerative arthropathies, particularly rheumatoid and osteoarthritis. The Centre offers refurbished laboratories, cutting edge facilities and is located in the heart of the City of London in close proximity to the Barbican Arts and Music Centre. 

Candidates should have a PhD degree or equivalent qualification in relevant subject and the main key areas of research include:

  • The principle aim of the project is to study the ontogeny of follicular dendritic cells (FDCs) in secondary lymphoid tissues and tertiary lymphoid structures. The specific objectives are:
  • Identification of the FDC precursors in human and murine secondary and tertiary lymphoid tissues.
  • In vitro generation of FDCs from the identified precursors.
  • A key element of this work is to assess the capacity of the in vitro generated FDCs and their precursors to induce B cell receptor- (BCR)-mediated B cell activation and antibody production in in vitro germinal centre reactions (GCRs).     

The post is full time and on a 6-month year fixed term contract. The starting salary will be £32,956 - £34,764 per annum inclusive of London Allowance. Benefits include 30 days annual leave and defined benefit pension scheme.

Candidates must be able to demonstrate their eligibility to work in the UK in accordance with the Immigration, Asylum and Nationality Act 2006. Where required this may include entry clearance or continued leave to remain under the Points Based Immigration Scheme.

Informal enquiries about this post are welcome and can be made to Dr M El Shikh ( or +44 (0)20 7882 8202.

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The closing date for the applications is 11th October 2017.

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